Life Sciences Collaborative Access Team

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HKL-2000 - program suite for oscillation data processing

The HKL-2000 suite of programs is designed to analyze X-ray diffraction data collected from single crystals. The programs have been written by Dr. Zbyszek Otwinowski (Southwestern Medical Center, University of Texas) and Dr. Wladek Minor (University of Virginia). The suite of programs on the NE-CAT beamlines are provided on the basis of scientific collaboration. The HKL-2000  package development is supported by the NIH grant GM-53163 to the laboratories of Professors Otwinowski and Minor.

Programs included in the HKL-2000 suite

DENZO_3D - Auto-indexing, refinement and integration
XDISPLAYF - Image display and measurement
SCALEPACK - Data scaling
STRAT - Strategy and simulation
HKLINT - Graphical Command Center


The use of the software package should be referenced in publication as follows:
Z. Otwinowski and W. Minor "Processing of X-ray Diffraction Data Collected in Oscillation Mode", Methods in Enzymology, Volume 276: Macromolecular Crystallography, part A, p. 307-326, 1997, C.W. Carter, Jr. and R.M. Sweet, Eds., Academic Press.

User Information

Experimenters who perform non-commercial research may freely use the program for data evaluation and processing while collecting data at the beamline. These experimenters can also obtain a temporary, free of charge, license to (re)process data collected at synchrotron beamlines. This license can be obtained by contacting HKL Research, Inc. Additional infortion about the HKL-2000 package may also be found at that site.

Our agreement to use this software package does not apply to commercial research. To obtain a commercial HKL license, please see: